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Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models

Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models
A tetravalent dwell attenuated dengue vaccine, Dengvaxia, sensitised naïve recipients to extreme dengue sickness upon a subsequent pure dengue an infection and is suspected to be as a consequence of antibody-dependent enhancement (ADE). ADE has additionally been implicated within the extreme neurological outcomes of Zika virus (ZIKV) an infection. It has change into evident that cross-reactive antibodies focusing on the viral pre-membrane protein and fusion-loop epitope are ADE-competent. A pre-clinical tetravalent dengue sub-unit vaccine candidate, DSV4, eliminates these ADE-competent epitopes.
We in contrast protecting efficacy and ADE-competence of murine polyclonal antibodies induced by DSV4, Dengvaxia and an ‘in home’ tetravalent combination of all 4 laboratory DENV strains, TV DENV, utilizing established mouse fashions. DSV4-induced antibodies, recognized to be predominantly type-specific, offered important safety in opposition to deadly DENV problem, however didn’t promote ADE of both DENV or ZIKV an infection in vivo. Antibodies elicited by Dengvaxia and TV DENV, that are predominantly cross-reactive, not solely failed to supply safety in opposition to deadly DENV problem, but in addition promoted ADE of each DENV and ZIKV an infection in vivo.
Protecting efficacy in opposition to DENV an infection could also be linked to the induction of neutralising antibodies that are type-specific moderately than cross-reactive. Complete virus-based dengue vaccines could also be related to ADE threat, regardless of their potent virus-neutralising capability. Vaccines designed to remove ADE-competent epitopes could assist remove/minimise ADE threat. This examine was supported partly by ICGEB, India, the Nationwide Biopharma Mission, DBT, Authorities of India, Solar Pharmaceutical Industries Restricted, India, and NIAID, NIH, USA.
Imlifidase, a cysteine protease derived from the immunoglobulin G (IgG)‑degrading enzyme of Streptococcus (S.) pyogenes is being developed by Hansa Biopharma AB for remedy of transplant rejection and uncommon IgG-mediated autoimmune circumstances. In August 2020, intravenous imlifidase acquired its first international approval within the EU for desensitization remedy of extremely sensitized grownup kidney transplant sufferers with constructive crossmatch in opposition to an obtainable deceased donor. Imlifidase is at present present process scientific analysis for the prevention of kidney transplant rejection within the USA, Australia, France and Austria, and scientific growth is underway for anti-glomerular basement membrane illness, and for Guillain-Barre syndrome in France, the UK and the Netherlands. This text summarizes the milestones within the growth of imlifidase resulting in this primary approval for desensitization remedy of extremely sensitized grownup kidney transplant sufferers with constructive crossmatch in opposition to an obtainable deceased donor.

In the direction of sensible biomanufacturing: a perspective on latest developments in industrial measurement and monitoring applied sciences for bio-based manufacturing processes

The biomanufacturing business has now the chance to improve its manufacturing processes to be in concord with the most recent industrial revolution. Know-how creates capabilities that allow sensible manufacturing whereas nonetheless complying with unfolding laws. Nevertheless, many biomanufacturing corporations, particularly within the biopharma sector, nonetheless have an extended solution to go to completely profit from sensible manufacturing as they first have to transition their present operations to an information-driven future.
One of the vital important obstacles in the direction of the implementation of sensible biomanufacturing is the gathering of huge units of related information. Due to this fact, on this work, we each summarize the advances which have been made up to now almost about the monitoring and management of bioprocesses, and spotlight among the key applied sciences which have the potential to contribute to gathering large information. Empowering the present biomanufacturing business to transition to Trade 4.zero operations permits for improved productiveness by means of information-driven automation, not solely by creating infrastructure, but in addition by introducing extra superior monitoring and management methods.
Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models

Growth of laser-free, protein oxidation system, real-time radical dosimeter and information processing software program for HOS of proteins utilizing HRPF

Hydroxyl Radical Protein Foot printing (HRPF) is an rising larger order structural (HOS) evaluation method. Nevertheless, its broad-based adoption within the biopharma business has been restricted by vital components: the usage of costly & harmful lasers for photolysis; variation amongst back-ground scavenging HRPF samples; & the intensive and laborious information processing course of required to carry out the oxidation calculation of peptides. To handle these points, we created novel instrumentation & software program for automated calculation of the peptide oxidation. We developed a flash-oxidation (FOXTM) photolysis system that replaces UV lasers with a protected benchtop means to carry out laser free HRPF HOS evaluation. We validated this instrument by oxidizing apo-myoglobin at varied flash energies.
Experiments had been carried out with 1 mM adenine and 100 mM peroxide. An efficient real-time optical radical dosimeter, upon response with hydroxyl radicals, adenine loses UV absorbance at 265 nm. By monitoring ∆Abs265nm, the efficient hydroxyl radical focus delivered to pattern will be decided. To beat the issue of variation between replicates of the HRPF samples, we developed FOXTM Radical Dosimeter. Actual-time measurement of efficient hydroxyl radical yield by measuring adenine absorbance supplies reproducible labeling no matter background scavenging. Singly, doubly, & triply oxidized merchandise of apo-myoglobin had been generated. Oxidation merchandise are just like these generated by laser publicity of the samples. A radical dose dependence plot of peptide oxidation vs radical dosimetry indicated glorious labeling protection together with the absence of HOS labeling artifacts.

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

20-abx127002
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

20-abx002213
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx033651-400ul 400 ul
EUR 523

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx033651-80l 80 µl
EUR 286

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx015963-100ug 100 ug
EUR 411

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx015964-100ug 100 ug
EUR 411

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx241830
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx242867
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx213983
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx327762
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Rat Pdx1/ Pancreas/duodenum homeobox protein 1 ELISA Kit

E0744Ra 1 Kit
EUR 646

Human PDX1/ Pancreas/duodenum homeobox protein 1 ELISA Kit

E1899Hu 1 Kit
EUR 605

Mouse Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

abx520945-96tests 96 tests
EUR 668

Rat Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

abx520946-96tests 96 tests
EUR 668

Human Pancreas/duodenum homeobox protein 1 (PDX1) ELISA Kit

abx251794-96tests 96 tests
EUR 668

ELISA kit for Human Pancreas/duodenum homeobox protein 1

EK4887 96 tests
EUR 603
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Pancreas/duodenum homeobox protein 1 in samples from serum, plasma, tissue homogenates and other biological fluids.

Human PDX1(Pancreas/duodenum homeobox protein 1) ELISA Kit

EH2431 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human Pancreas/duodenum homeobox protein 1, PDX1 ELISA KIT

ELI-15305h 96 Tests
EUR 824

Mouse Pancreas/duodenum homeobox protein 1, Pdx1 ELISA KIT

ELI-16116m 96 Tests
EUR 865

Recombinant (E.Coli, His-tag) Human Pancreas S Duodenum Homeobox-1

RP-864 10 ug
EUR 225

Pdx1 ELISA Kit| Rat Pancreas/duodenum homeobox protein 1 ELISA

EF019128 96 Tests
EUR 689

Pdx1 ELISA Kit| Mouse Pancreas/duodenum homeobox protein 1 ELIS

EF015784 96 Tests
EUR 689

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Rabbit anti-sEH

SEH-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Anti-Homeobox protein SIX6 Antibody

A06502-1 100ug/vial
EUR 294

Motor neuron and pancreas homeobox protein 1 (MNX1) Antibody

20-abx338605
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Motor Neuron And Pancreas Homeobox Protein 1 (MNX1) Antibody

abx028845-400ul 400 ul
EUR 523

Motor Neuron And Pancreas Homeobox Protein 1 (MNX1) Antibody

abx028845-80l 80 µl
EUR 286

Motor Neuron And Pancreas Homeobox Protein 1 (MNX1) Antibody

20-abx216901
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Duodenum Lysate

1364 0.1 mg
EUR 191
Description: Duodenum tissue lysate was prepared by homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

CK PANCREAS POWDER LYOPH 10g*

43032-1 10g
EUR 333.61

Motor neuron and pancreas homeobox protein 1 (MNX1) Antibody (HRP)

20-abx336588
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Motor neuron and pancreas homeobox protein 1 (MNX1) Antibody (FITC)

20-abx336589
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Motor neuron and pancreas homeobox protein 1 (MNX1) Antibody (Biotin)

20-abx336590
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Paraffin Tissue Section - Human Small Intestine Tumor: Duodenum Adenocarcinoma

T2235226-1 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Mouse Mnx1/ Motor neuron and pancreas homeobox protein 1 ELISA Kit

E0966Mo 1 Kit
EUR 632

Human MNX1/ Motor neuron and pancreas homeobox protein 1 ELISA Kit

E1625Hu 1 Kit
EUR 605

Mouse Motor neuron and pancreas homeobox protein 1 (MNX1) ELISA Kit

abx516940-96tests 96 tests
EUR 739

Human Motor neuron and pancreas homeobox protein 1 (MNX1) ELISA Kit

abx250899-96tests 96 tests
EUR 739

ELISA kit for Human Motor neuron and pancreas homeobox protein 1

EK3406 96 tests
EUR 670
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Motor neuron and pancreas homeobox protein 1 in samples from serum, plasma, tissue homogenates and other biological fluids.

Human MNX1(Motor neuron and pancreas homeobox protein 1) ELISA Kit

EH1608 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.9pg/ml

Duodenum Membrane Lysate

XBL-10547 0.1 mg
EUR 516.5
Description: Human duodenum tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human duodenum tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated duodenum tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated duodenum tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Duodenum Tumor Lysate

1328 0.1 mg
EUR 254
Description: Duodenum tumor tissue lysate was prepared by homogenization in lysis buffer (50 mM Tris-HCl pH7.4, 150 mM NaCl, 1 mM PMSF, 1 mM EDTA, 5 μg/ml aprotinin, 5 μg/ml leupeptin, 1% Triton x-100, 1% DOC, 0.1% SDS). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Anti-Sumo 1 Rabbit Monoclonal Antibody

M00631-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Sumo 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Cytokeratin 1 Rabbit Monoclonal Antibody

M01639-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Cytokeratin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Rabbit PANCREAS Y 25 EA*

41231-2 25 EA
EUR 341.23

Rabbit PANCREAS MATURE 25 EA*

41331-2 25 EA
EUR 341.23

Paraffin Tissue Section - Human Pancreas Tumor: Adenocarcinoma

T2235188-1 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

ELISA kit for Mouse Motor neuron and pancreas homeobox protein 1 (MNX1)

KTE70989-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Mouse Motor neuron and pancreas homeobox protein 1 (MNX1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Motor neuron and pancreas homeobox protein 1 (MNX1)

KTE70989-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Mouse Motor neuron and pancreas homeobox protein 1 (MNX1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Motor neuron and pancreas homeobox protein 1 (MNX1)

KTE70989-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Mouse Motor neuron and pancreas homeobox protein 1 (MNX1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Motor neuron and pancreas homeobox protein 1 (MNX1)

KTE61575-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Human Motor neuron and pancreas homeobox protein 1 (MNX1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Motor neuron and pancreas homeobox protein 1 (MNX1)

KTE61575-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Human Motor neuron and pancreas homeobox protein 1 (MNX1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Motor neuron and pancreas homeobox protein 1 (MNX1)

KTE61575-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Human Motor neuron and pancreas homeobox protein 1 (MNX1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Anti-HMGB1/Hmg 1 Rabbit Monoclonal Antibody

M00066-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal HMGB1/Hmg 1 Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-p27 KIP 1 Rabbit Monoclonal Antibody

M00173-1 100ug/vial
EUR 397
Description: Anti-p27 KIP 1 Rabbit Monoclonal Antibody tested for Flow Cytometry, IP, IF, IHC, ICC, WB in Human, Rat

Anti-MHC class 1 Rabbit Monoclonal Antibody

M00194-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal MHC class 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human.

Anti-Integrin beta 1 Rabbit Monoclonal Antibody

M00772-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Integrin beta 1 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-ARG1/Arginase 1 Rabbit Monoclonal Antibody

M01106-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal ARG1/Arginase 1 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat.

Anti-MLANA/Mart 1 Rabbit Monoclonal Antibody

M02033-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal MLANA/Mart 1 Antibody. Validated in IF, WB and tested in Human.

Anti-DSG1/Desmoglein 1 Rabbit Monoclonal Antibody

M02655-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal DSG1/Desmoglein 1 Antibody. Validated in IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Polyclonal Goat Anti-Homeobox B13 Antibody

APG00160G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-Homeobox B13 . This antibody is tested and proven to work in the following applications:

Anti-CETP Antibody (polyclonal rabbit anti-human, mouse, rat) with goat anti-rabbit HRP secondary antibody

EXOAB-CETP-1 25 ul
EUR 219

Human Duodenum Tumor lysate

HTL-1328 1 mg
EUR 895

Duodenum Diabetic Disease Lysate

XBL-10336 0.1 mg
EUR 663.5
Description: Human duodenum tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human duodenum tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the duodenum tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The duodenum tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Duodenum Liver Cirrhosis Lysate

XBL-10337 0.1 mg
EUR 663.5
Description: Human duodenum tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human duodenum tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the duodenum tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The duodenum tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Anti-AFP/Alpha 1 Fetoprotein Rabbit Monoclonal Antibody

M00522-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal AFP/Alpha 1 Fetoprotein Antibody. Validated in IP, IF, WB and tested in Human.

Anti-SERPINA1/Alpha 1 Antitrypsin Rabbit Monoclonal Antibody

M00720-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal SERPINA1/Alpha 1 Antitrypsin Antibody. Validated in IP, IF, WB and tested in Human.

Anti-GPX1/Glutathione Peroxidase 1 Rabbit Monoclonal Antibody

M01019-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal GPX1/Glutathione Peroxidase 1 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat.

Anti-BAG-1 Rabbit Monoclonal Antibody, Clone#RM356

M02423-1 100uL
EUR 385
Description: Anti-BAG-1 Rabbit Monoclonal Antibody, Clone#RM356 tested in WB, IHC, reactive to Human

Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378

M04431-1 100uL
EUR 385
Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human

Pancreas Lysate

1414 0.1 mg
EUR 191
Description: Pancreas tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Pancreas Lysate

1469 0.1 mg
EUR 191
Description: Pancreas tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Pancreas Lysate

1307 0.1 mg
EUR 191
Description: Pancreas tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Anti-Phospho-AMPK alpha 1 (S496) Rabbit Monoclonal Antibody

P00994-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Phospho-AMPK alpha 1 (S496) Antibody. Validated in IP, IF, WB and tested in Human.

Anti-MEK3 Rabbit Monoclonal Antibody

M02916-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal MEK3 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

Anti-NSE Rabbit Monoclonal Antibody

M02930-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal NSE Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-Hsp47 Rabbit Monoclonal Antibody

M03050-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Hsp47 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Calnexin Rabbit Monoclonal Antibody

M03372-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Calnexin Antibody. Validated in IF, WB and tested in Human, Rat.

Anti-RNF20 Rabbit Monoclonal Antibody

M03457-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal RNF20 Antibody. Validated in IP, IF, WB and tested in Human, Mouse.

Anti-Cubilin Rabbit Monoclonal Antibody

M03670-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Cubilin Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-CD20 Rabbit Monoclonal Antibody

M03780-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal CD20 Antibody. Validated in IHC, WB and tested in Human.

Anti-ADFP Rabbit Monoclonal Antibody

M04328-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal ADFP Antibody. Validated in Flow Cytometry, IF, ICC, WB and tested in Human, Mouse, Rat.

Anti-CD11a Rabbit Monoclonal Antibody

M04466-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal CD11a Antibody. Validated in IP, IF, WB and tested in Human.

Anti-Caldesmon Rabbit Monoclonal Antibody

M04578-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Caldesmon Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

Anti-Rab4 Rabbit Monoclonal Antibody

M04643-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Rab4 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-Synaptophysin Rabbit Monoclonal Antibody

M05049-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Synaptophysin Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-JunD Rabbit Monoclonal Antibody

M05609-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal JunD Antibody. Validated in IP, IF, WB and tested in Human.

Anti-HAPLN1 Rabbit Monoclonal Antibody

M05980-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal HAPLN1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-RAIDD Rabbit Monoclonal Antibody

M06509-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal RAIDD Antibody. Validated in IP, IF, WB and tested in Human.

Anti-5T4 Rabbit Monoclonal Antibody

M07442-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal 5T4 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat.

Anti-KDEL Rabbit Monoclonal Antibody

M07617-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal KDEL Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Calponin Rabbit Monoclonal Antibody

M08065-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Calponin Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-IgG4 Rabbit Monoclonal Antibody

M11385-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal IgG4 Antibody. Validated in IHC, WB and tested in Human.

Anti-GFP Rabbit Monoclonal Antibody

M30939-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal GFP Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-p53 Rabbit Monoclonal Antibody

M00001-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal p53 Antibody. Validated in IP, IF, WB and tested in Human.

Anti-PTEN Rabbit Monoclonal Antibody

M00006-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal PTEN Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

Anti-STAT3 Rabbit Monoclonal Antibody

M00007-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal STAT3 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-BDNF Rabbit Monoclonal Antibody

M00035-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal BDNF Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-STAT1 Rabbit Monoclonal Antibody

M00036-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal STAT1 Antibody. Validated in IP, WB and tested in Human, Mouse.

Anti-VEGF Rabbit Monoclonal Antibody

M00045-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal VEGF Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC and tested in Human, Mouse.

Anti-CD44 Rabbit Monoclonal Antibody

M00052-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal CD44 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse.

Anti-Insulin Rabbit Monoclonal Antibody

M00067-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Insulin Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-Rad51 Rabbit Monoclonal Antibody

M00088-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Rad51 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Smad2 Rabbit Monoclonal Antibody

M00090-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Smad2 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-Tau Rabbit Monoclonal Antibody

M00097-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Tau Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

Anti-SOX2 Rabbit Monoclonal Antibody

M00105-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal SOX2 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse.

Anti-Src Rabbit Monoclonal Antibody

M00107-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Src Antibody. Validated in IF, WB and tested in Human, Rat.

Anti-PCNA Rabbit Monoclonal Antibody

M00125-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal PCNA Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-CD11b Rabbit Monoclonal Antibody

M00144-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal CD11b Antibody. Validated in IF, IHC, ICC, WB and tested in Human, Mouse.

Anti-SHP2 Rabbit Monoclonal Antibody

M00150-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal SHP2 Antibody. Validated in IP, WB and tested in Human, Mouse, Rat.

Anti-CD19 Rabbit Monoclonal Antibody

M00154-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal CD19 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-CDK4 Rabbit Monoclonal Antibody

M00159-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal CDK4 Antibody. Validated in IF, WB and tested in Human.

Anti-p63 Rabbit Monoclonal Antibody

M00167-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal p63 Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-PD1 Rabbit Monoclonal Antibody

M00178-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal PD1 Antibody. Validated in IHC and tested in Human.

Anti-Bax Rabbit Monoclonal Antibody

M00183-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Bax Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat.

Anti-NCAM Rabbit Monoclonal Antibody

M00184-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal NCAM Antibody. Validated in IP, IF, WB and tested in Human.

Anti-TRAF6 Rabbit Monoclonal Antibody

M00185-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal TRAF6 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-MUC1 Rabbit Monoclonal Antibody

M00187-1 100ug/vial
EUR 397
Description: Anti-MUC1 Rabbit Monoclonal Antibody tested for Flow Cytometry, IP, IF, IHC, ICC, WB in Human

Anti-FGFR3 Rabbit Monoclonal Antibody

M00200-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal FGFR3 Antibody. Validated in IF, WB and tested in Human.

Anti-GFAP Rabbit Monoclonal Antibody

M00213-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal GFAP Antibody. Validated in IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-LRRK2 Rabbit Monoclonal Antibody

M00221-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal LRRK2 Antibody. Validated in IF, WB and tested in Human, Mouse.

Anti-GAPDH Rabbit Monoclonal Antibody

M00227-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal GAPDH Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Canine, Chicken, Cow, Human, Monkey, Mouse, Rat.

Anti-Vimentin Rabbit Monoclonal Antibody

M00235-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Vimentin Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-CD147 Rabbit Monoclonal Antibody

M00248-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal CD147 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-FoxO3a Rabbit Monoclonal Antibody

M00252-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal FoxO3a Antibody. Validated in IF, IHC, WB and tested in Human.

Anti-MMP2 Rabbit Monoclonal Antibody

M00286-1 100ug/vial
EUR 397
Description: Anti-MMP2 Rabbit Monoclonal Antibody tested for IHC-P, WB in Human, Mouse, Rat.

Anti-Tyrosinase Rabbit Monoclonal Antibody

M00326-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Tyrosinase Antibody. Validated in IF, WB and tested in Human.

Anti-CD11c Rabbit Monoclonal Antibody

M00357-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal CD11c Antibody. Validated in IP, IF, IHC, ICC, WB and tested in Human.
A significant facet limiting the large utilization of HRPF is the guide, time-consuming calculation of peptide oxidation & lack of any automated information processing software program. We developed FoxWareTM evaluation Software program for the speedy and dependable quantitation of peptide quantification of HRPF information, encouraging utilization in biopharma.

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