Artificial biology is a quickly rising interdisciplinary analysis discipline that’s primarily constructed upon foundational advances in molecular biology mixed with engineering design. The sector considers dwelling techniques as programmable on the genetic stage and has been outlined by the event of latest platform applied sciences. This has spurned a fast progress in start-up corporations and the brand new artificial biology {industry} is rising quickly, with start-up corporations receiving ∼$6.1B funding since 2015 and a world artificial biology market worth estimated to be $14B by 2026.
Most of the new start-ups will be grouped inside a multi-layer ‘expertise stack’. The ‘stack’ includes quite a few expertise layers which collectively will be utilized to a variety of latest biotechnology purposes like shopper biotechnology merchandise and dwelling therapies. The ‘stack’ additionally allows new business alternatives and worth chains just like the software program design and manufacturing revolution of the 20th century. Nonetheless, the artificial biology {industry} is at a vital level, because it now requires recognisable business successes to ensure that the {industry} to broaden and scale, when it comes to funding and firms. Nonetheless, such growth might instantly problem the ethos of artificial biology, when it comes to open expertise sharing and democratisation, which may unintentionally result in multi-national firms and expertise monopolies just like the prevailing biotechnology/biopharma {industry}.
Course of Optimization and Switch of Freeze-drying in Nested Vial Programs
Scale-up and switch of freeze-drying processes is a vital problem in biopharma {industry}. With the success of small batch processing traces using rack vial holding techniques, additional detailed information about freeze-drying cycles and their scale-up for vials in a rack is required. Subsequently, product temperature (TP) profiles in addition to Kv values of vials nested in a Polyetheretherketon (PEEK) rack have been in comparison with these of vials positioned in a generally used chrome steel tray.
Moreover, each setups have been challenged with various fill quantity and partially versus absolutely loaded rack. Moreover, a course of developed for rack was in comparison with a tray freeze-drying cycle. Freeze-drying in vials positioned within the rack is markedly sooner for middle vials and extra homogeneous in comparison with vials in bulk tray setting, as indicated by TP and Kv values. Because of the extra homogeneous drying the rack is extra versatile relating to variation of the fill quantity. The important thing level for the switch of a freeze-drying cycle from rack to tray is to think about the upper sublimation charges within the rack by adapting chamber stress or shelf temperature for the tray. Moreover, switch from one rack per shelf in a laboratory freeze-dryer to pilot scale with 4 racks per shelf was profitable. Thus, understanding of the method in rack and tray setup was enhanced to make sure environment friendly scale-up and switch of freeze-drying processes.
Glycosylation impacts the properties of biologics; thus regulatory our bodies categorized it as crucial high quality attribute and drive biopharma {industry} to seize and management it all through all phases, from R&D until finish of product lifetime. The shift from originators to biosimilars additional will increase significance and extent of glycoanalysis, which thus will increase the necessity for expertise platforms enabling dependable high-throughput and in-depth glycan evaluation. On this chapter, we are going to first summarize on established glycoanalytical strategies based mostly on liquid chromatography specializing in hydrophilic interplay chromatography, capillary electrophoresis specializing in multiplexed capillary gel electrophoresis, and mass spectrometry specializing in matrix-assisted laser desorption; we are going to then spotlight two rising applied sciences based mostly on porous graphitized carbon liquid chromatography and on ion-mobility mass spectrometry as each are extremely promising instruments to ship an extra stage of data for in-depth glycan evaluation;
moreover we elaborate on the benefits and challenges of various glycoanalytical applied sciences and their complementarity; lastly, we briefly overview purposes thereof to biopharmaceutical merchandise. This chapter gives an outline of present state-of-the-art analytical approaches for glycan characterization of biopharmaceuticals that may be employed to seize glycoprotein heterogeneity in a biopharmaceutical context.
Enhancing goal evaluation in biomedical analysis: the GOT-IT suggestions
Educational analysis performs a key function in figuring out new drug targets, together with understanding goal biology and hyperlinks between targets and illness states. To result in new medication, nonetheless, analysis should progress from purely educational exploration to the initiation of efforts to determine and check a drug candidate in medical trials, that are sometimes performed by the biopharma {industry}. This transition will be facilitated by a well timed deal with goal evaluation points similar to target-related issues of safety, druggability and assayability, in addition to the potential for goal modulation to realize differentiation from established therapies.
ASAH2 Polyclonal Antibody |
E-AB-62491-120uL |
Elabscience Biotech |
120uL |
EUR 320 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-62491-200uL |
Elabscience Biotech |
200uL |
EUR 530 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-62491-60uL |
Elabscience Biotech |
60uL |
EUR 200 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-62491-each |
Elabscience Biotech |
each |
Ask for price |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-14747-120uL |
Elabscience Biotech |
120uL |
EUR 240 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-14747-200uL |
Elabscience Biotech |
200uL |
EUR 399 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-14747-20uL |
Elabscience Biotech |
20uL |
EUR 73 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-14747-60uL |
Elabscience Biotech |
60uL |
EUR 143 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-10960-120uL |
Elabscience Biotech |
120uL |
EUR 240 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-10960-200uL |
Elabscience Biotech |
200uL |
EUR 399 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-10960-20uL |
Elabscience Biotech |
20uL |
EUR 73 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-10960-60uL |
Elabscience Biotech |
60uL |
EUR 143 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-64270-120uL |
Elabscience Biotech |
120uL |
EUR 320 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-64270-200uL |
Elabscience Biotech |
200uL |
EUR 530 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-64270-60uL |
Elabscience Biotech |
60uL |
EUR 200 |
|
Description: Unconjugated |
ASAH2 Polyclonal Antibody |
E-AB-64270-each |
Elabscience Biotech |
each |
Ask for price |
|
Description: Unconjugated |
Polyclonal ASAH2 Antibody |
APG02010G |
Leading Biology |
0.1 mg |
EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ASAH2 . This antibody is tested and proven to work in the following applications: |
Polyclonal ASAH2 Antibody |
APG02011G |
Leading Biology |
0.1mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ASAH2 . This antibody is tested and proven to work in the following applications: |
ASAH3 Rabbit Polyclonal Antibody |
ES8356-100ul |
ELK Biotech |
100ul |
EUR 124 |
|
Description: A Rabbit Polyclonal antibody against ASAH3 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA |
ASAH3 Rabbit Polyclonal Antibody |
ES8356-50ul |
ELK Biotech |
50ul |
EUR 74 |
|
Description: A Rabbit Polyclonal antibody against ASAH3 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA |
ASAH1 Rabbit Polyclonal Antibody |
E10G08026 |
EnoGene |
100 μl |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
ASAH3 Rabbit Polyclonal Antibody |
E10G23389 |
EnoGene |
100 μl |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
ASAH1 Rabbit Polyclonal Antibody |
E10G01084 |
EnoGene |
100 μl |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
ASAH3L Rabbit Polyclonal Antibody |
ES8419-100ul |
ELK Biotech |
100ul |
EUR 124 |
|
Description: A Rabbit Polyclonal antibody against ASAH3L from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
ASAH3L Rabbit Polyclonal Antibody |
ES8419-50ul |
ELK Biotech |
50ul |
EUR 74 |
|
Description: A Rabbit Polyclonal antibody against ASAH3L from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
ASAH3L Rabbit Polyclonal Antibody |
E10G23259 |
EnoGene |
100 μl |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
ASAH2 Polyclonal Antibody, HRP Conjugated |
A62107 |
EpiGentek |
-
Ask for price
-
Ask for price
-
Ask for price
|
|
ASAH2 Polyclonal Antibody, FITC Conjugated |
A62108 |
EpiGentek |
-
Ask for price
-
Ask for price
-
Ask for price
|
|
ASAH2 Polyclonal Antibody, Biotin Conjugated |
A62109 |
EpiGentek |
-
Ask for price
-
Ask for price
-
Ask for price
|
|
Polyclonal Antibody to N-Acylsphingosine Amidohydrolase 2 (ASAH2) |
PAE689Hu01 |
Cloud-Clone |
100ul |
EUR 245 |
|
Polyclonal Antibody to N-Acylsphingosine Amidohydrolase 2 (ASAH2) |
PAE689Ra02 |
Cloud-Clone |
100ul |
EUR 266 |
|
Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (IHC) |
IRBAMLASAH2AP491120UL |
Innovative research |
each |
EUR 346 |
|
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (IHC) |
Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (IHC) |
IRBAMLASAH2AP491200UL |
Innovative research |
each |
EUR 509 |
|
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (IHC) |
Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot) |
IRBAMLASAH2AP270120UL |
Innovative research |
each |
EUR 346 |
|
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot) |
Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot) |
IRBAMLASAH2AP270200UL |
Innovative research |
each |
EUR 509 |
|
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot) |
Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA) |
IRBAMLASAH2AP747120UL |
Innovative research |
each |
EUR 259 |
|
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA) |
Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA) |
IRBAMLASAH2AP747200UL |
Innovative research |
each |
EUR 403 |
|
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA) |
Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA) |
IRBAMLASAH2AP960120UL |
Innovative research |
each |
EUR 259 |
|
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA) |
Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA) |
IRBAMLASAH2AP960200UL |
Innovative research |
each |
EUR 403 |
|
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA) |
ASAH2 Rabbit pAb |
E2507985 |
EnoGene |
100ul |
EUR 225 |
Description: Available in various conjugation types. |
ASAH2 Rabbit pAb |
E2511158 |
EnoGene |
100ul |
EUR 225 |
Description: Available in various conjugation types. |
ASAH2 Rabbit pAb |
A12596-100ul |
Abclonal |
100 ul |
EUR 369.6 |
ASAH2 Rabbit pAb |
A12596-200ul |
Abclonal |
200 ul |
EUR 550.8 |
ASAH2 Rabbit pAb |
A12596-20ul |
Abclonal |
20 ul |
EUR 219.6 |
ASAH2 Rabbit pAb |
A12596-50ul |
Abclonal |
50 ul |
EUR 267.6 |
ASAH2 Rabbit pAb |
A7985-100ul |
Abclonal |
100 ul |
EUR 369.6 |
ASAH2 Rabbit pAb |
A7985-200ul |
Abclonal |
200 ul |
EUR 550.8 |
ASAH2 Rabbit pAb |
A7985-20ul |
Abclonal |
20 ul |
EUR 219.6 |
ASAH2 Rabbit pAb |
A7985-50ul |
Abclonal |
50 ul |
EUR 267.6 |
ASAH2 Rabbit pAb |
E2821910 |
EnoGene |
100ul |
EUR 225 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
ASAH2 Rabbit pAb |
E2121910 |
EnoGene |
100ul |
EUR 225 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
ASAH1 Polyclonal Antibody |
E913948 |
EnoGene |
100ul |
EUR 225 |
Description: Available in various conjugation types. |
ASAH3 Polyclonal Antibody |
E20-75672 |
EnoGene |
100ug |
EUR 225 |
Description: Available in various conjugation types. |
ASAH3 Polyclonal Antibody |
ABP57363-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of ASAH3 from Human. This ASAH3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3 at AA range: 100-180 |
ASAH3 Polyclonal Antibody |
ABP57363-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of ASAH3 from Human. This ASAH3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3 at AA range: 100-180 |
ASAH3 Polyclonal Antibody |
ABP57363-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of ASAH3 from Human. This ASAH3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3 at AA range: 100-180 |
ASAH3 Polyclonal Antibody |
E44H07114 |
EnoGene |
100ul |
EUR 255 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
ASAH1 Polyclonal Antibody |
E-AB-14746-120uL |
Elabscience Biotech |
120uL |
EUR 240 |
|
Description: Unconjugated |
ASAH1 Polyclonal Antibody |
E-AB-14746-200uL |
Elabscience Biotech |
200uL |
EUR 399 |
|
Description: Unconjugated |
ASAH1 Polyclonal Antibody |
E-AB-14746-20uL |
Elabscience Biotech |
20uL |
EUR 73 |
|
Description: Unconjugated |
ASAH1 Polyclonal Antibody |
E-AB-14746-60uL |
Elabscience Biotech |
60uL |
EUR 143 |
|
Description: Unconjugated |
ASAH1 Polyclonal Antibody |
E-AB-10959-120uL |
Elabscience Biotech |
120uL |
EUR 240 |
|
Description: Unconjugated |
ASAH1 Polyclonal Antibody |
E-AB-10959-200uL |
Elabscience Biotech |
200uL |
EUR 399 |
|
Description: Unconjugated |
ASAH1 Polyclonal Antibody |
E-AB-10959-20uL |
Elabscience Biotech |
20uL |
EUR 73 |
|
Description: Unconjugated |
ASAH1 Polyclonal Antibody |
E-AB-10959-60uL |
Elabscience Biotech |
60uL |
EUR 143 |
|
Description: Unconjugated |
ASAH3L Polyclonal Antibody |
E20-75673 |
EnoGene |
100ug |
EUR 225 |
Description: Available in various conjugation types. |
ASAH3L Polyclonal Antibody |
44025 |
SAB |
100ul |
EUR 319 |
ASAH3L Polyclonal Antibody |
ABP57426-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of ASAH3L from Human, Mouse. This ASAH3L antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3L at AA range: 50-130 |
ASAH3L Polyclonal Antibody |
ABP57426-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of ASAH3L from Human, Mouse. This ASAH3L antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3L at AA range: 50-130 |
ASAH3L Polyclonal Antibody |
ABP57426-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of ASAH3L from Human, Mouse. This ASAH3L antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3L at AA range: 50-130 |
ASAH3L Polyclonal Antibody |
E44H07115 |
EnoGene |
100ul |
EUR 255 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
Polyclonal ASAH1 Antibody |
APG02008G |
Leading Biology |
0.1 mg |
EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ASAH1 . This antibody is tested and proven to work in the following applications: |
Polyclonal ASAH3L Antibody |
APR15065G |
Leading Biology |
0.1ml |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ASAH3L . This antibody is tested and proven to work in the following applications: |
ASAM Rabbit Polyclonal Antibody |
E10G31206 |
EnoGene |
100 μl |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
ASAP2 Rabbit Polyclonal Antibody |
ES8991-100ul |
ELK Biotech |
100ul |
EUR 124 |
|
Description: A Rabbit Polyclonal antibody against ASAP2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
ASAP2 Rabbit Polyclonal Antibody |
ES8991-50ul |
ELK Biotech |
50ul |
EUR 74 |
|
Description: A Rabbit Polyclonal antibody against ASAP2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
ASAH2 Antibody |
24731 |
SAB |
100ul |
EUR 479 |
ASAH2 Antibody |
24731-100ul |
SAB |
100ul |
EUR 468 |
ASAH2 Antibody |
3828-100 |
Biovision |
each |
EUR 379.2 |
ASAH2 Antibody |
3828-30T |
Biovision |
each |
EUR 175.2 |
ASAH2 Antibody |
4743-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: ASAH2 Antibody: Sphingolipids are hydrolyzed by ceramidases to yield sphingosine and fatty acids. These ceramidases are classified according to the pH range that supports their optimal activity. ASAH2 is a neutral ceramidase and key regulator of sphingolipid signaling metabolites at the cell surface, catalyzing the hydrolysis of the N-acyl linkage of ceramide at an optimal pH of 6.5-8.5. ASAH2 is a type II integral membrane protein that can be cleaved to yield a soluble secreted protein and acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger. ASAH2 is ubiquitously expressed primarily expressed with higher levels in the intestine, kidney, skeletal muscle and heart. Recent studies indicate that ASAH2 encoded neutral ceramidase is a key enzyme for the catabolism of dietary sphingolipids and regulates the levels of bioactive sphingolipid metabolites in the intestinal tract. |
ASAH2 Antibody |
4743-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: ASAH2 Antibody: Sphingolipids are hydrolyzed by ceramidases to yield sphingosine and fatty acids. These ceramidases are classified according to the pH range that supports their optimal activity. ASAH2 is a neutral ceramidase and key regulator of sphingolipid signaling metabolites at the cell surface, catalyzing the hydrolysis of the N-acyl linkage of ceramide at an optimal pH of 6.5-8.5. ASAH2 is a type II integral membrane protein that can be cleaved to yield a soluble secreted protein and acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger. ASAH2 is ubiquitously expressed primarily expressed with higher levels in the intestine, kidney, skeletal muscle and heart. Recent studies indicate that ASAH2 encoded neutral ceramidase is a key enzyme for the catabolism of dietary sphingolipids and regulates the levels of bioactive sphingolipid metabolites in the intestinal tract. |
ASAH2 Antibody |
E036240 |
EnoGene |
100μg/100μl |
EUR 255 |
Description: Available in various conjugation types. |
ASAH2 Antibody |
F40044-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
|
Description: Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]). |
ASAH2 Antibody |
F40044-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
|
Description: Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]). |
ASAH2 Antibody |
E912596 |
EnoGene |
100ul |
EUR 255 |
Description: Available in various conjugation types. |
ASAH2 Antibody |
E97985 |
EnoGene |
100ul |
EUR 255 |
Description: Available in various conjugation types. |
ASAH2 Antibody |
1-CSB-PA002170EA01HU |
Cusabio |
-
Ask for price
-
Ask for price
|
|
|
Description: A polyclonal antibody against ASAH2. Recognizes ASAH2 from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:500, IF:1:50-1:500 |
ASAH2 Antibody |
36240 |
SAB |
100ul |
EUR 319 |
ASAH2 Antibody |
36240-100ul |
SAB |
100ul |
EUR 302.4 |
ASAH2 antibody |
70R-12124 |
Fitzgerald |
100 ug |
EUR 343 |
|
Description: Rabbit polyclonal ASAH2 antibody |
ASAH2 Antibody |
1-CSB-PA076840 |
Cusabio |
-
Ask for price
-
Ask for price
|
|
|
Description: A polyclonal antibody against ASAH2. Recognizes ASAH2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
ASAH2 Antibody |
1-CSB-PA133826 |
Cusabio |
-
Ask for price
-
Ask for price
|
|
|
Description: A polyclonal antibody against ASAH2. Recognizes ASAH2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
ASAP3 (N-term) Rabbit Polyclonal Antibody |
E10G30890 |
EnoGene |
100 μl |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
Rabbit Polyclonal AntibodyPC4 Rabbit Polyclonal Antibody |
54946 |
SAB |
100ul |
EUR 439 |
Rabbit Polyclonal AntibodyPC1 Rabbit Polyclonal Antibody |
53940 |
SAB |
100ul |
EUR 439 |
Polyclonal ASAH1 / Acid Ceramidase Antibody (C-Terminus) |
APG02006G |
Leading Biology |
0.05mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ASAH1 / Acid Ceramidase (C-Terminus). This antibody is tested and proven to work in the following applications: |
Right here, we current suggestions from the GOT-IT working group, which have been designed to assist educational scientists and funders of translational analysis in figuring out and prioritizing goal evaluation actions and in defining a crucial path to achieve scientific targets in addition to targets associated to licensing, partnering with {industry} or initiating medical growth programmes. Primarily based on units of guiding questions for various areas of goal evaluation, the GOT-IT framework is meant to stimulate educational scientists’ consciousness of things that make translational analysis extra sturdy and environment friendly, and to facilitate academia-industry collaboration.