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Synthetic biology industry: data-driven design is creating new opportunities in biotechnology

Synthetic biology industry: data-driven design is creating new opportunities in biotechnology

Artificial biology is a quickly rising interdisciplinary analysis discipline that’s primarily constructed upon foundational advances in molecular biology mixed with engineering design. The sector considers dwelling techniques as programmable on the genetic stage and has been outlined by the event of latest platform applied sciences. This has spurned a fast progress in start-up corporations and the brand new artificial biology {industry} is rising quickly, with start-up corporations receiving ∼$6.1B funding since 2015 and a world artificial biology market worth estimated to be $14B by 2026.

Most of the new start-ups will be grouped inside a multi-layer ‘expertise stack’. The ‘stack’ includes quite a few expertise layers which collectively will be utilized to a variety of latest biotechnology purposes like shopper biotechnology merchandise and dwelling therapies. The ‘stack’ additionally allows new business alternatives and worth chains just like the software program design and manufacturing revolution of the 20th century. Nonetheless, the artificial biology {industry} is at a vital level, because it now requires recognisable business successes to ensure that the {industry} to broaden and scale, when it comes to funding and firms. Nonetheless, such growth might instantly problem the ethos of artificial biology, when it comes to open expertise sharing and democratisation, which may unintentionally result in multi-national firms and expertise monopolies just like the prevailing biotechnology/biopharma {industry}.

Course of Optimization and Switch of Freeze-drying in Nested Vial Programs

Scale-up and switch of freeze-drying processes is a vital problem in biopharma {industry}. With the success of small batch processing traces using rack vial holding techniques, additional detailed information about freeze-drying cycles and their scale-up for vials in a rack is required. Subsequently, product temperature (TP) profiles in addition to Kv values of vials nested in a Polyetheretherketon (PEEK) rack have been in comparison with these of vials positioned in a generally used chrome steel tray.
Moreover, each setups have been challenged with various fill quantity and partially versus absolutely loaded rack. Moreover, a course of developed for rack was in comparison with a tray freeze-drying cycle. Freeze-drying in vials positioned within the rack is markedly sooner for middle vials and extra homogeneous in comparison with vials in bulk tray setting, as indicated by TP and Kv values. Because of the extra homogeneous drying the rack is extra versatile relating to variation of the fill quantity. The important thing level for the switch of a freeze-drying cycle from rack to tray is to think about the upper sublimation charges within the rack by adapting chamber stress or shelf temperature for the tray. Moreover, switch from one rack per shelf in a laboratory freeze-dryer to pilot scale with 4 racks per shelf was profitable. Thus, understanding of the method in rack and tray setup was enhanced to make sure environment friendly scale-up and switch of freeze-drying processes.
Glycosylation impacts the properties of biologics; thus regulatory our bodies categorized it as crucial high quality attribute and drive biopharma {industry} to seize and management it all through all phases, from R&D until finish of product lifetime. The shift from originators to biosimilars additional will increase significance and extent of glycoanalysis, which thus will increase the necessity for expertise platforms enabling dependable high-throughput and in-depth glycan evaluation. On this chapter, we are going to first summarize on established glycoanalytical strategies based mostly on liquid chromatography specializing in hydrophilic interplay chromatography, capillary electrophoresis specializing in multiplexed capillary gel electrophoresis, and mass spectrometry specializing in matrix-assisted laser desorption; we are going to then spotlight two rising applied sciences based mostly on porous graphitized carbon liquid chromatography and on ion-mobility mass spectrometry as each are extremely promising instruments to ship an extra stage of data for in-depth glycan evaluation;
moreover we elaborate on the benefits and challenges of various glycoanalytical applied sciences and their complementarity; lastly, we briefly overview purposes thereof to biopharmaceutical merchandise. This chapter gives an outline of present state-of-the-art analytical approaches for glycan characterization of biopharmaceuticals that may be employed to seize glycoprotein heterogeneity in a biopharmaceutical context.
Synthetic biology industry: data-driven design is creating new opportunities in biotechnology

Enhancing goal evaluation in biomedical analysis: the GOT-IT suggestions

Educational analysis performs a key function in figuring out new drug targets, together with understanding goal biology and hyperlinks between targets and illness states. To result in new medication, nonetheless, analysis should progress from purely educational exploration to the initiation of efforts to determine and check a drug candidate in medical trials, that are sometimes performed by the biopharma {industry}. This transition will be facilitated by a well timed deal with goal evaluation points similar to target-related issues of safety, druggability and assayability, in addition to the potential for goal modulation to realize differentiation from established therapies.

ASAH2 Polyclonal Antibody

E-AB-62491-120uL 120uL
EUR 320
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-62491-200uL 200uL
EUR 530
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-62491-60uL 60uL
EUR 200
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-62491-each each Ask for price
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-14747-120uL 120uL
EUR 240
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-14747-200uL 200uL
EUR 399
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-14747-20uL 20uL
EUR 73
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-14747-60uL 60uL
EUR 143
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-10960-120uL 120uL
EUR 240
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-10960-200uL 200uL
EUR 399
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-10960-20uL 20uL
EUR 73
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-10960-60uL 60uL
EUR 143
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-64270-120uL 120uL
EUR 320
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-64270-200uL 200uL
EUR 530
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-64270-60uL 60uL
EUR 200
Description: Unconjugated

ASAH2 Polyclonal Antibody

E-AB-64270-each each Ask for price
Description: Unconjugated

Polyclonal ASAH2 Antibody

APG02010G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ASAH2 . This antibody is tested and proven to work in the following applications:

Polyclonal ASAH2 Antibody

APG02011G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ASAH2 . This antibody is tested and proven to work in the following applications:

ASAH3 Rabbit Polyclonal Antibody

ES8356-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against ASAH3 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

ASAH3 Rabbit Polyclonal Antibody

ES8356-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against ASAH3 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

ASAH1 Rabbit Polyclonal Antibody

E10G08026 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

ASAH3 Rabbit Polyclonal Antibody

E10G23389 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

ASAH1 Rabbit Polyclonal Antibody

E10G01084 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

ASAH3L Rabbit Polyclonal Antibody

ES8419-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against ASAH3L from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

ASAH3L Rabbit Polyclonal Antibody

ES8419-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against ASAH3L from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

ASAH3L Rabbit Polyclonal Antibody

E10G23259 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Rabbit Polyclonal ASAH1 Antibody

TA306621 100 µg Ask for price

ASAH2 Polyclonal Antibody, HRP Conjugated

A62107
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 µg
  • 50 ul
  • 100 ul

ASAH2 Polyclonal Antibody, FITC Conjugated

A62108
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 µg
  • 50 ul
  • 100 ul

ASAH2 Polyclonal Antibody, Biotin Conjugated

A62109
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 µg
  • 50 ul
  • 100 ul

Rabbit polyclonal anti-ACER1 (ASAH3) antibody

TA316075 100 µl Ask for price

Polyclonal Antibody to N-Acylsphingosine Amidohydrolase 2 (ASAH2)

PAE689Hu01 100ul
EUR 245

Polyclonal Antibody to N-Acylsphingosine Amidohydrolase 2 (ASAH2)

PAE689Ra02 100ul
EUR 266

Rabbit Polyclonal Anti-ASAH2 Antibody

TA349659 100 µl Ask for price

Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (IHC)

IRBAMLASAH2AP491120UL each
EUR 346
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (IHC)

Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (IHC)

IRBAMLASAH2AP491200UL each
EUR 509
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (IHC)

Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot)

IRBAMLASAH2AP270120UL each
EUR 346
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot)

Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot)

IRBAMLASAH2AP270200UL each
EUR 509
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot)

Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA)

IRBAMLASAH2AP747120UL each
EUR 259
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA)

Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA)

IRBAMLASAH2AP747200UL each
EUR 403
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA)

Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA)

IRBAMLASAH2AP960120UL each
EUR 259
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA)

Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA)

IRBAMLASAH2AP960200UL each
EUR 403
Description: Rabbit Anti ASAH2 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA)

ASAH2 Rabbit pAb

E2507985 100ul
EUR 225
Description: Available in various conjugation types.

ASAH2 Rabbit pAb

E2511158 100ul
EUR 225
Description: Available in various conjugation types.

ASAH2 Rabbit pAb

A12596-100ul 100 ul
EUR 369.6

ASAH2 Rabbit pAb

A12596-200ul 200 ul
EUR 550.8

ASAH2 Rabbit pAb

A12596-20ul 20 ul
EUR 219.6

ASAH2 Rabbit pAb

A12596-50ul 50 ul
EUR 267.6

ASAH2 Rabbit pAb

A7985-100ul 100 ul
EUR 369.6

ASAH2 Rabbit pAb

A7985-200ul 200 ul
EUR 550.8

ASAH2 Rabbit pAb

A7985-20ul 20 ul
EUR 219.6

ASAH2 Rabbit pAb

A7985-50ul 50 ul
EUR 267.6

ASAH2 Rabbit pAb

E2821910 100ul
EUR 225
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

ASAH2 Rabbit pAb

E2121910 100ul
EUR 225
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

ASAH1 Polyclonal Antibody

E913948 100ul
EUR 225
Description: Available in various conjugation types.

ASAH3 Polyclonal Antibody

E20-75672 100ug
EUR 225
Description: Available in various conjugation types.

ASAH3 Polyclonal Antibody

ABP57363-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of ASAH3 from Human. This ASAH3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3 at AA range: 100-180

ASAH3 Polyclonal Antibody

ABP57363-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of ASAH3 from Human. This ASAH3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3 at AA range: 100-180

ASAH3 Polyclonal Antibody

ABP57363-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of ASAH3 from Human. This ASAH3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3 at AA range: 100-180

ASAH3 Polyclonal Antibody

E44H07114 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

ASAH1 Polyclonal Antibody

E-AB-14746-120uL 120uL
EUR 240
Description: Unconjugated

ASAH1 Polyclonal Antibody

E-AB-14746-200uL 200uL
EUR 399
Description: Unconjugated

ASAH1 Polyclonal Antibody

E-AB-14746-20uL 20uL
EUR 73
Description: Unconjugated

ASAH1 Polyclonal Antibody

E-AB-14746-60uL 60uL
EUR 143
Description: Unconjugated

ASAH1 Polyclonal Antibody

E-AB-10959-120uL 120uL
EUR 240
Description: Unconjugated

ASAH1 Polyclonal Antibody

E-AB-10959-200uL 200uL
EUR 399
Description: Unconjugated

ASAH1 Polyclonal Antibody

E-AB-10959-20uL 20uL
EUR 73
Description: Unconjugated

ASAH1 Polyclonal Antibody

E-AB-10959-60uL 60uL
EUR 143
Description: Unconjugated

ASAH3L Polyclonal Antibody

E20-75673 100ug
EUR 225
Description: Available in various conjugation types.

ASAH3L Polyclonal Antibody

44025 100ul
EUR 319

ASAH3L Polyclonal Antibody

ABP57426-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of ASAH3L from Human, Mouse. This ASAH3L antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3L at AA range: 50-130

ASAH3L Polyclonal Antibody

ABP57426-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of ASAH3L from Human, Mouse. This ASAH3L antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3L at AA range: 50-130

ASAH3L Polyclonal Antibody

ABP57426-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of ASAH3L from Human, Mouse. This ASAH3L antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ASAH3L at AA range: 50-130

ASAH3L Polyclonal Antibody

E44H07115 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Polyclonal ASAH1 Antibody

APG02008G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ASAH1 . This antibody is tested and proven to work in the following applications:

Polyclonal ASAH3L Antibody

APR15065G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ASAH3L . This antibody is tested and proven to work in the following applications:

ASAM Rabbit Polyclonal Antibody

E10G31206 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

ASAP2 Rabbit Polyclonal Antibody

ES8991-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against ASAP2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

ASAP2 Rabbit Polyclonal Antibody

ES8991-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against ASAP2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

ASAH2 Antibody

24731 100ul
EUR 479

ASAH2 Antibody

24731-100ul 100ul
EUR 468

ASAH2 Antibody

3828-100 each
EUR 379.2

ASAH2 Antibody

3828-30T each
EUR 175.2

ASAH2 Antibody

4743-002mg 0.02 mg
EUR 206.18
Description: ASAH2 Antibody: Sphingolipids are hydrolyzed by ceramidases to yield sphingosine and fatty acids. These ceramidases are classified according to the pH range that supports their optimal activity. ASAH2 is a neutral ceramidase and key regulator of sphingolipid signaling metabolites at the cell surface, catalyzing the hydrolysis of the N-acyl linkage of ceramide at an optimal pH of 6.5-8.5. ASAH2 is a type II integral membrane protein that can be cleaved to yield a soluble secreted protein and acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger. ASAH2 is ubiquitously expressed primarily expressed with higher levels in the intestine, kidney, skeletal muscle and heart. Recent studies indicate that ASAH2 encoded neutral ceramidase is a key enzyme for the catabolism of dietary sphingolipids and regulates the levels of bioactive sphingolipid metabolites in the intestinal tract.

ASAH2 Antibody

4743-01mg 0.1 mg
EUR 523.7
Description: ASAH2 Antibody: Sphingolipids are hydrolyzed by ceramidases to yield sphingosine and fatty acids. These ceramidases are classified according to the pH range that supports their optimal activity. ASAH2 is a neutral ceramidase and key regulator of sphingolipid signaling metabolites at the cell surface, catalyzing the hydrolysis of the N-acyl linkage of ceramide at an optimal pH of 6.5-8.5. ASAH2 is a type II integral membrane protein that can be cleaved to yield a soluble secreted protein and acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger. ASAH2 is ubiquitously expressed primarily expressed with higher levels in the intestine, kidney, skeletal muscle and heart. Recent studies indicate that ASAH2 encoded neutral ceramidase is a key enzyme for the catabolism of dietary sphingolipids and regulates the levels of bioactive sphingolipid metabolites in the intestinal tract.

ASAH2 Antibody

E036240 100μg/100μl
EUR 255
Description: Available in various conjugation types.

ASAH2 Antibody

F40044-0.08ML 0.08 ml
EUR 140.25
Description: Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).

ASAH2 Antibody

F40044-0.4ML 0.4 ml
EUR 322.15
Description: Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).

ASAH2 Antibody

E912596 100ul
EUR 255
Description: Available in various conjugation types.

ASAH2 Antibody

E97985 100ul
EUR 255
Description: Available in various conjugation types.

ASAH2 Antibody

DF15667 100ul
EUR 420

ASAH2 Antibody

DF15667-100ul 100ul
EUR 280

ASAH2 Antibody

DF15667-200ul 200ul
EUR 350

ASAH2 Antibody

1-CSB-PA002170EA01HU
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against ASAH2. Recognizes ASAH2 from Human, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:500, IF:1:50-1:500

ASAH2 Antibody

36240 100ul
EUR 319

ASAH2 Antibody

36240-100ul 100ul
EUR 302.4

ASAH2 antibody

70R-12124 100 ug
EUR 343
Description: Rabbit polyclonal ASAH2 antibody

ASAH2 Antibody

CAC11754-100ug 100ug
EUR 314

ASAH2 Antibody

CAC11754-50ug 50ug
EUR 199.2

ASAH2 Antibody

1-CSB-PA076840
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against ASAH2. Recognizes ASAH2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

ASAH2 Antibody

1-CSB-PA133826
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against ASAH2. Recognizes ASAH2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

ASAP3 (N-term) Rabbit Polyclonal Antibody

E10G30890 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Rabbit Polyclonal AntibodyPC4 Rabbit Polyclonal Antibody

54946 100ul
EUR 439

Rabbit Polyclonal AntibodyPC1 Rabbit Polyclonal Antibody

53940 100ul
EUR 439

Rabbit polyclonal Uplc1/Asap3 antibody

TA319368 100 µg Ask for price

Rabbit Polyclonal Anti-BAG4 rabbit polyclonal antibody

TA351743 100 µl Ask for price

Rabbit Polyclonal Anti-LPP rabbit polyclonal antibody

TA351364 100 µl Ask for price

Rabbit Polyclonal Anti-TPR rabbit polyclonal antibody

TA351467 100 µl Ask for price

Rabbit Polyclonal Anti-RORA rabbit polyclonal antibody

TA351609 100 µl Ask for price

Rabbit Polyclonal Anti-SSX5 rabbit polyclonal antibody

TA351758 100 µl Ask for price

Rabbit Polyclonal Anti-TGM7 rabbit polyclonal antibody

TA351848 100 µl Ask for price

Rabbit Polyclonal Anti-SRPX rabbit polyclonal antibody

TA350419 100 µl Ask for price

Rabbit Polyclonal Anti-STX7 rabbit polyclonal antibody

TA350469 100 µl Ask for price

Rabbit Polyclonal Anti-STX8 rabbit polyclonal antibody

TA350470 100 µl Ask for price

Rabbit Polyclonal Anti-NOX5 rabbit polyclonal antibody

TA350234 100 µl Ask for price

Polyclonal ASAH1 / Acid Ceramidase Antibody (C-Terminus)

APG02006G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ASAH1 / Acid Ceramidase (C-Terminus). This antibody is tested and proven to work in the following applications:

Rabbit Polyclonal Anti-CERS3 rabbit polyclonal antibody

TA351342 100 µl Ask for price

Rabbit Polyclonal Anti-LLGL2 rabbit polyclonal antibody

TA351357 100 µl Ask for price

Rabbit Polyclonal Anti-PSMB8 rabbit polyclonal antibody

TA351358 100 µl Ask for price

Rabbit Polyclonal Anti-LONP1 rabbit polyclonal antibody

TA351359 100 µl Ask for price

Rabbit Polyclonal Anti-LOXL2 rabbit polyclonal antibody

TA351360 100 µl Ask for price

Rabbit Polyclonal Anti-LOXL3 rabbit polyclonal antibody

TA351362 100 µl Ask for price

Rabbit Polyclonal Anti-LOXL4 rabbit polyclonal antibody

TA351363 100 µl Ask for price

Rabbit Polyclonal Anti-LZTS1 rabbit polyclonal antibody

TA351367 100 µl Ask for price

Rabbit Polyclonal Anti-MACC1 rabbit polyclonal antibody

TA351368 100 µl Ask for price

Rabbit Polyclonal Anti-SMYD5 rabbit polyclonal antibody

TA351731 100 µl Ask for price

Rabbit Polyclonal Anti-TRPV5 rabbit polyclonal antibody

TA351861 100 µl Ask for price

Rabbit Polyclonal Anti-TRPV3 rabbit polyclonal antibody

TA351862 100 µl Ask for price

Rabbit Polyclonal Anti-ROBO4 rabbit polyclonal antibody

TA350367 100 µl Ask for price

Rabbit Polyclonal Anti-RRAGA rabbit polyclonal antibody

TA350374 100 µl Ask for price

Rabbit Polyclonal Anti-SAMD7 rabbit polyclonal antibody

TA350388 100 µl Ask for price

Rabbit Polyclonal Anti-SEPP1 rabbit polyclonal antibody

TA350395 100 µl Ask for price

Rabbit Polyclonal Anti-SENP8 rabbit polyclonal antibody

TA350399 100 µl Ask for price

Rabbit Polyclonal Anti-SENP5 rabbit polyclonal antibody

TA350400 100 µl Ask for price

Rabbit Polyclonal Anti-SMYD3 rabbit polyclonal antibody

TA350428 100 µl Ask for price

Rabbit Polyclonal Anti-SMYD4 rabbit polyclonal antibody

TA350429 100 µl Ask for price

Rabbit Polyclonal Anti-SNAI3 rabbit polyclonal antibody

TA350430 100 µl Ask for price

Rabbit Polyclonal Anti-STX18 rabbit polyclonal antibody

TA350473 100 µl Ask for price

Rabbit Polyclonal Anti-STX11 rabbit polyclonal antibody

TA350476 100 µl Ask for price

Rabbit Polyclonal Anti-STX19 rabbit polyclonal antibody

TA350477 100 µl Ask for price

Rabbit Polyclonal Anti-TBX18 rabbit polyclonal antibody

TA350485 100 µl Ask for price

Rabbit Polyclonal Anti-TBX10 rabbit polyclonal antibody

TA350486 100 µl Ask for price

Rabbit Polyclonal Anti-EFNB3 rabbit polyclonal antibody

TA350660 100 µl Ask for price

Rabbit Polyclonal Anti-FOXG1 rabbit polyclonal antibody

TA350672 100 µl Ask for price

Rabbit Polyclonal Anti-SPARC rabbit polyclonal antibody

TA349441 100 µl Ask for price

Rabbit Polyclonal Anti-OLFM3 rabbit polyclonal antibody

TA350251 100 µl Ask for price

Rabbit Polyclonal Anti-OLFM4 rabbit polyclonal antibody

TA350252 100 µl Ask for price

Rabbit Polyclonal Anti-LTB4R2 rabbit polyclonal antibody

TA351366 100 µl Ask for price

Rabbit Polyclonal Anti-AGPAT9 rabbit polyclonal antibody

TA351369 100 µl Ask for price

Rabbit Polyclonal Anti-MAGEB2 rabbit polyclonal antibody

TA351371 100 µl Ask for price

Rabbit Polyclonal Anti-SLC7A5 rabbit polyclonal antibody

TA351714 100 µl Ask for price

Rabbit Polyclonal Anti-AGPAT6 rabbit polyclonal antibody

TA351863 100 µl Ask for price

Rabbit Polyclonal Anti-PRSS50 rabbit polyclonal antibody

TA351865 100 µl Ask for price

Rabbit Polyclonal Anti-PTPMT1 rabbit polyclonal antibody

TA350308 100 µl Ask for price

Rabbit Polyclonal Anti-DHCR24 rabbit polyclonal antibody

TA350394 100 µl Ask for price

Rabbit Polyclonal Anti-SEMA4A rabbit polyclonal antibody

TA350396 100 µl Ask for price
Right here, we current suggestions from the GOT-IT working group, which have been designed to assist educational scientists and funders of translational analysis in figuring out and prioritizing goal evaluation actions and in defining a crucial path to achieve scientific targets in addition to targets associated to licensing, partnering with {industry} or initiating medical growth programmes. Primarily based on units of guiding questions for various areas of goal evaluation, the GOT-IT framework is meant to stimulate educational scientists’ consciousness of things that make translational analysis extra sturdy and environment friendly, and to facilitate academia-industry collaboration.

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